As shown in Figure 4A−C, THE heatmap respectively displayed the correlations between WDR6 and tumor‐infiltrating immune inhibitor, immunostimulator, and MCH molecules in pan‐cancer, and the scatter plots of the top 3 of the absolute value of p in LUAD patients, including PDCD1, IL10R, HAVCR2, CD86, TNFSF4, TNFSF13B, B2M, HLA‐DRA, and TAP1, and in LUSC patients including IL10RB, PDCD1LG2, TGFBR2, CD48, TNFRSF25, TNFSF13B, B2M, HLA‐DRA, and HLA‐DRB1 respectively were showed. This evidence concerns the gene HLA-DRB1 and cancer.