Asshown in Table S1, logistic regression analysis revealed that patients with ahigher TXNIP level had a greater risk of PD-A, PD-B, or T2D in the subgroup withlow IRAK-M (<3.76 ng/mL), before and after adjusting for confounding factors(all p < 0.05). This evidence concerns the gene IRAK3 and type 2 diabetes mellitus.