IRAK-M andmetabolic parameters, including fasting insulin (FINS), glycosylatedhemoglobin (HbA1c), homeostasis model assessment of insulin resistance(HOMA-IR) and beta-cell function (HOMA-β), and thioredoxin-interactingprotein (TXNIP), were evaluated. The gene discussed is IRAK1; the disease is Insulin resistance.