IFNG and abortion: Interestingly, IFN-γ serum level was observed to be lower in mice that treated with ZIL suggesting its proinflammatory effect but in a study done by Kim et al. [34], transient production of this cytokine during the placental developmental period induces B. abortus-induced abortion in ICR mice indicating the promising benefit of ZIL in the prevention of abortion in animals although more investigations are necessary to prove this claim.