For instance, Zhu et al. reported that the cytoplasmic circRNA circZKSCSN1 could suppress the malignant behavior of hepatocellular carcinoma by competitively binding with the RBP FMRP, thereby interfering with the interaction between FMRP protein and CCAR1 mRNAs [40]. This evidence concerns the gene FMR1 and hepatocellular carcinoma.