We also found an elevation of frequencies of Th17 cells and serum level of proinflammatory IL17A and significant increase in serum level of anti-inflammatory IL-10, in agreement with the findings of increased serum levels of IL-6, TNF-α, IL-1β, IL-2, and IL-10 in PD patients from a meta-analysis of 25 studies and 2654 participants [5]. This evidence concerns the gene IL1B and Parkinson disease.