TSPO and Parkinson disease: Taking advantage of lower impact of the rs6971 polymorphism of TSPO gene in the Chinese population, the current study has evaluated (i) the central microglia activation in PD using the second-generation TSPO radioligand 18F-PBR06; (ii) the relationship between central microglia activation, disease severity and dopaminergic denervation; (iii) the associations between the central microglia activation and peripheral inflammatory.