NPPB and pulmonary arterial hypertension: The ESC/ERS guidelines recommend the use of NT-proBNP as a part of a multiparameter prognostic assessment for prognosis and as a treatment goal for PAH patients and provide thresholds to define low (< 300 ng/L), moderate (300–1400 ng/L) and high-risk (> 1400 ng/L) NT-proBNP levels [4].