Then, we performed dual-luciferase reporter assays in HCC cells and found that the luciferase activity was significantly downregulated after increasing the hsa-miR-765 expression in MHCC97H and HCCLM3 cells transfected with lncRNA-AC079061.1 or VIPR1 wildtype vectors. This evidence concerns the gene VIPR1 and hepatocellular carcinoma.