Adiponectin suppresses cell proliferation in oestrogen receptor positive (MCF7) and negative (MDA-MB 231) breast cancer cells as well as hepatocellular (HepG2, Huh7) and endometrial (HEC-1-A, RL95-2) cancer cell lines [110–113] and its drop in obesity may contribute to cancer cells evading growth suppression. The gene discussed is ADIPOQ; the disease is obesity disorder.