Based on collinearity among variables and clinical redundancy we further focused on a subset of 13 variables (age, gender, COPD, diabetes, hypertension, oxygen saturation, creatinine, CRP, Liver steatosis, well-aerated lung volume, main pulmonary artery diameter, vertebral attenuation and total cardiovascular thoracic calcium). The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.