CEACAM5 and neoplasm: However, age (p = 0.021), tumor location (p < 0.001), chemotherapy (p = 0.026), alkaline phosphatase (p = 0.016), total bilirubin (p = 0.016), direct bilirubin (p = 0.021), carcinoembryonic antigen (p = 0.019), and carbohydrate antigen 125 (p = 0.004) showed significant differences between the two subtypes.