Another study on ferroptosis-related long non-coding RNA (lncRNA) found that patients in the high-risk group had a better response to drugs targeting PI3K/AKT, WNT signaling, and the cytoskeleton, suggesting that aberrant activation of signaling pathways such as PI3K/AKT may inhibit ferroptosis in gastric cancer cells [74]. This evidence concerns the gene AKT1 and gastric cancer.