IL1B and isolated hemihyperplasia: SC-2 identifies a mildly inflamed region; the endpoint phenotypes obtained are as before: V (77%), A (10%), and IH (13%), but with IH becoming dominant over A. The third scenario (Fig 2C), with IL-6, IL-1β and IFN-I, identifies a portion of the tissue with an ongoing cytokine storm (or strong inflammatory response).