We found that a GWAS association of diverticular disease [59], which is a condition that involves small pockets called diverticula that form from the wall of the colon, showed high colocalization probability with the puQTL association for prmtr.109751 (PP4 = 0.90); however, we observed no colocalization with the eQTL association for the MAPKAP1 gene (PP4 = 0.091) (Fig 4H), indicating that standard eQTL studies cannot detect this variant–gene–trait association. This evidence concerns the gene MAPKAP1 and diverticular disease.