Interestingly, in comparison with this purified plant recombinant protein different concentrations of commercial CCL21 were used according to the standard curve of %TSP, where CCL21/IL1β antigen promoted its toxic effects at a concentration of 7.5 μg/ml, the survival rate of cancer cells was 22.1%, and IC50 was 0.315 μg/ml (Fig 7B). This evidence concerns the gene IL1B and cancer.