CD8A and HIV infectious disease: Although ART has converted HIV infection from a mortal disease to a chronic controllable condition by dramatically suppressing viral replication (Wing, 2016), immunosenescence‐like changes including the expansion of memory CD8+ T cells with senescent features are reported in young HIV‐infected individuals who do not have clinically detectable viremia on ART (Desai & Landay, 2010; Regidor et al., 2011; Warren et al., 2019).