Some studies outlined an association of elevated levels of biomarkers such as Ang-1, sTREM-1, CXCL10, and sICAM-1, with prolonged clinical recovery times in patients having survived from Pf-SM disease [56], while other putative biomarkers were not found to be associated with Pf-SM-related clinical recovery and time [57]. Here, CXCL10 is linked to systemic mastocytosis.