EGFR and breast carcinoma: Furthermore, in breast cancer, EGCG inhibits tumor invasion and angiogenesis by suppressing VEGF expression, as well as inhibiting epidermal growth factor receptor (EGFR) and ERK1/2 phosphorylation levels, which also supports the use of HSP70 inhibitors as radiosensitizers for tumors (Khan and Mukhtar, 2010).