FOLH1 and posterior cortical atrophy: Figure 1 shows how radiolabeled ligands bind with PSMA on PCa cells and serve as imaging and radioligands therapeutic tools. Moreover, quantitative parameters derived from PSMA-based PET/CT alone or from the combination with 18-fluorodeoxyglucose (18F-FDG) PET/CT have been proven to be predictive of the outcome of patients before receiving RLT, thereby improving the selection of the best choice of management option and drug at an individual level.