DMD and hypertrophic cardiomyopathy: Additionally, KEGG pathways associated with protein digestion and absorption, dilated and hypertrophic cardiomyopathy, ECM-receptor interaction, and cGMP-PKG signalling pathway (known to positively modulates cardiac contractility, hypertrophy and protects against apoptosis (Takimoto, 2012) were significantly enriched in DMD-COs (Table 4 and Figure 6E (i)).