Moreover, we argued that the presence of GDF10 near the PDGFRα+ fibroblast/adipocyte progenitors could be a feedback regulation mechanism to inhibit pathological formation of adipose tissues in the DMD-COs, as GDF10 was not detected in DMD-Iso-COs where adipogenesis did not occur. The gene discussed is PDGFRA; the disease is Duchenne muscular dystrophy.