AGT and hypertensive disorder: In an angiotensin II (Ang II)-induced rat hypertension model, intramedullary infusion of sodium butyrate lowered mean arterial pressure by suppressing renal receptor (PRR)-mediated intrarenal rennin-angiotensin system indicated by the renal expression of PRR, angiotensinogen, angiotensin I-converting enzyme and rennin (72).