ACADVL and idiopathic dilated cardiomyopathy: Protein levels of very long-chain acyl CoA dehydrogenase (VLCAD) were decreased in LV tissue from male BTHS subjects compared to age-matched, non-failing male subjects and male subjects diagnosed with idiopathic dilated cardiomyopathy, as assessed by both immunoblotting and LC-MS/MS based proteomic profiling (20).