VCAM1 and Cowden syndrome 1: Treatment with RAAS inhibitors prior to admission was associated with tendentially lower concentrations of S-VCAM-1 [1717 (1108; 2332) vs. 3524 (2141; 5252) ng/ml, p = 0.058, Supplementary Table S1] in CS patients at admission, but no significant changes were detected in other time points or in other endothelial cell adhesion molecules or in AHF patients (Supplementary Table S1).