Figure 1A shows results for the transcripts of intact RA and OA tissue and demonstrates heterogeneity, with expected overlap between OA (n = 10) and RA (n = 5). However, IL-1ß, MCP1 and CXCL10 significantly distinguished OA and RA cohorts (corrected p = 0.007, 0.029, and 0.015, respectively) in our patient sample. This evidence concerns the gene CCL2 and rheumatoid arthritis.