CD8A and Hodgkins lymphoma: The percentage of CD4+ T cells (median, 28.82%, range, 10.55–56.07%, Z = −3.912, p = 0.001) and CD4+/CD8+ ratio (median, 1.01, range, 0.17–2.90, Z = −4.846, p < 0.001) decreased significantly in patients with HL compared to healthy controls.