AR and diabetes mellitus: Multivariate Cox proportional hazards modeling showed that after adjusting for DM, previous peritonitis episode and 24h urine volume, higher baseline dialysate IL-6 AR levels (HR 3.639, 95% CI 1.776–7.456, P = 0.002) were associated with an increased risk of UF insufficiency after being corrected for multiple testing (see Table 5).