There are 2 SNPs overlaps between adult obesity and childhood BMI, namely, rs987237 (TFAP2B) and rs13130484 (GNPDA2), but no overlaps were found in birth weight, adult obesity and childhood BMI, which means that some childhood obesity may continue into adulthood, while birth weight has a limited effect on childhood or adult obesity. The gene discussed is GNPDA2; the disease is obesity due to melanocortin 4 receptor deficiency.