In this study, an open and open data platform was used to detect DEGs in postmortem prefrontal cortex and peripheral blood samples from AD patients and healthy controls and the regression coefficients of 0 without the LASSO model (MT1X, IGF1, DLEU7, TRIM36, PTPRC, WNK2, SPG20, C8orf59, BRWD1). This evidence concerns the gene TRIM36 and Alzheimer disease.