In this study, an open and open data platform was used to detect DEGs in postmortem prefrontal cortex and peripheral blood samples from AD patients and healthy controls and the regression coefficients of 0 without the LASSO model (MT1X, IGF1, DLEU7, TRIM36, PTPRC, WNK2, SPG20, C8orf59, BRWD1). Here, BRWD1 is linked to Alzheimer disease.