MKI67 and metastatic malignant neoplasm in the lymph nodes: There were statistically significant differences in age, tumor pathological type, primary tumor site, Ki-67 index, TNM stage, lymph node metastasis, and distant metastasis between the two groups (all P < 0.05), while other factors like gender was not related to the prognosis of patients with GP-NENs (all P > 0.05) (Table 1).