IL17A and proximal spinal muscular atrophy: In serum of adult SMA patients, a significant decrease in the levels of IL-4 (p < 0.05), IL-6 (p < 0.05), INF-γ (p < 0.05), and IL-17A (p < 0.05) after 6 months of treatment compared to baseline values was found (Figures 1, 2).