Carrier and segregation analysis of BAB6263 identified a homozygous variant in general transcription factor IIIC subunit 1 (GTF3C1: c.4096G>A [p.Glu1366Lys]), and this particular GTF3C1 variant allele has been reported previously by our group, causing cerebellar atrophy in another unrelated Turkish kindred (Figure S3).17 The gene discussed is GTF3C1; the disease is Cerebellar atrophy.