KNTC1 and adenocarcinoma: Finally, we investigated whether the expression of MCM4, CENPI, and KNTC1 was associated with the NEPC score, which was introduced to quantify the degree of CRPC-adenocarcinoma (CRPC-Adeno) conversion to CRPC-neuroendocrine (CRPC-NE), a more aggressive variant of CRPC.