Furthermore, EGFR, IGF1, PTGS2, FGF1, CAV1, and PLCB1, were verified to be expressed differentially in PABC compared with normal tissues, and IGF1, PTGS2, and FGF1 were demonstrated to be significantly related to breast cancer patient prognosis, suggesting that the three genes might serve as biomarkers for precision diagnosis and treatment of PABC. The gene discussed is PLCB1; the disease is breast cancer.