Gene ontology and enrichment analyses further indicated that the DEGs in PABC versus NPABC were mainly enriched in pathways in cancer, the PI3K-Akt signaling pathway, focal adhesion, the Rap1 signaling pathway, proteoglycans in cancer, microRNAs in cancer, prostate cancer, the p53 signaling pathway, small cell lung cancer, and melanoma and glioma pathways. This evidence concerns the gene AKT1 and melanoma.