Besides, as presented in Figure 4D, high CD8A expression was correlated to longer survival time of patients in CTLA4-treated melanoma cohort (VanAllen2015_CTLA4), PD1-treated melanoma cohort (Gide2019_PD1), PDL1-treated metastatic bladder cancer cohort (Mariathasan2018_PDL1), and PD1-treated NSCLC-HNSC-Melanoma cohort (Prat2017_PD1). This evidence concerns the gene CTLA4 and non-small cell lung carcinoma.