Results indicated that CD8A were invariably negatively correlated with MDSCs in most cancer and subtypes, including bladder urothelial carcinoma (BLCA), BRCA, COAD, ESCA, HNSC, KIRC, KIRP, KICH, LUAD, LUSC, mesothelioma (MESO), ovarian serous cystadenocarcinoma (OV), PAAD, metastatic pheochromocytoma and paraganglioma (PCPG), PRAD, READ, SARC, SKCM, stomach adenocarcinoma (STAD), TGCT, THCA, UCEC, and UVM. This evidence concerns the gene CD8A and bladder transitional cell carcinoma.