The results disclosed that CD8A presented higher methylation levels in tumor tissues of multiple cancer types, including BLCA, BRCA, cholangiocarcinoma (CHOL), COAD, ESCA, HNSC, KIRC, KIRP, LUAD, LIHC, LUSC, PAAD, PRAD, READ, and UCEC, compared to its corresponding normal control (Figure 5A). Here, CD8A is linked to bladder transitional cell carcinoma.