CD8A and cancer: Following that, we dissected the correlation between CD8A expression level and the overall survival of pan-cancer patients, indicating that low CD8A expression may have deleterious effects on the prognosis of specific cancer types (Figure 3B), including thymoma (THYM), head and neck squamous cell carcinoma (HNSC), uterine corpus endometrial carcinoma (UCEC), BRCA, skin cutaneous melanoma (SKCM), cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC).