As for the reason behind, we think that CTRP9 level may affect liver cholesterol synthesis and decomposition or blood sugar tolerance, resulting in local oxidative stress injury or local stress injury caused by blood lipid metabolism disorder, thereby promoting local ovarian epithelial endocrine functional disorders in PCOS patients, inhibiting ovulation and inducing excessive androgen secretion and further facilitating progress of PCOS in patients. Here, C1QTNF9 is linked to polycystic ovary syndrome.