In addition, this study also found the following correlations between serum vaspin and lipid metabolism and obesity of PCOS patients: serum vaspin is positively correlated with BMI, WHR, FINS, TG, TC, LDL-C, HOMA-IR, and TT levels and negatively correlated with HDL-C (P < 0.05). Here, SERPINA12 is linked to obesity due to melanocortin 4 receptor deficiency.