Furthermore, based on the TCGA dataset, mRNA expression of ARID1A, ARID1B, ARID2, ARID3A, ARID3B, ARID4B, KDM5A, KDM5B, KDM5C, KDM5D, and JARID2 was remarkably overexpressed, and ARID3C and ARID4A were underexpressed in HCC (Figure 2). This evidence concerns the gene KDM5D and hepatocellular carcinoma.