GLP1R and Hyperglycemia: At the same time, it can scavenge for reactive oxygen species to exert its antioxidant effects, reducing oxidative damage to pancreatic β cells (Figure 8) (117); (III) Using healthy mice and obese diabetic mice models, Iwasaki et al. found that psicose promotes the release of GLP-1 and stimulates the GLP-1 receptor to affect the vagal afferent nerve, which enhances the development of satiety, thereby inhibiting food intake and reducing hyperglycemia (118).