In addition, the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is essential for NSCLC cell proliferation and tumor development (Tan, 2020) Also, PI3K/Akt signaling was reported to master the expression and location of GLUT1 (Wieman et al., 2007). Here, SLC2A1 is linked to non-small cell lung carcinoma.