MYH6 and familial dilated cardiomyopathy: However, various factors, such as ischemia, viral infection, and alcohol toxicity, could cause DCM, though the variants in genes encoding sarcomeric proteins, for example, myosin heavy chain-β and -α (MYH7 and MYH6), and the myosin light chain MYL2 were also implicated in DCM (Kamisago et al., 2000; Yuan et al., 2018).