PIK3CA and colorectal carcinoma: The results of qRT-PCR and Western blotting experiments showed that the mRNA and protein expressions of PI3K (3.26 ± 0.32), Akt (2.98 ± 0.29), and mTOR (3.16 ± 0.30) were all upregulated in CRC cells, and the difference was statistically significant (p < 0.05).