Moreover, DCBLD2 upregulation was associated with worse PD1 outcomes in glioblastoma (ICB_Zhao2019_PD1) and melanoma (ICB_Riaz2017_PD1 and ICB_Liu2019_PD1), worse CTLA4 outcomes in melanoma (ICB_Nathanson2017_CTLA4), and worse PDL1 outcomes in the bladder (ICB_Mariathasan2018_PDL1). This evidence concerns the gene CTLA4 and melanoma.