The results of the multiple logistic regression analyses showed that urine NT-proBNP levels between DOL 7 and 28 were substantially related to the development of BPD (odds ratio = 2.070–7.199, P < 0.05), and that BPD may be predicted in preterm infants as early as the first week after birth. This evidence concerns the gene NPPB and bronchopulmonary dysplasia.