It has been shown that platelets of COVID-19 patients release significantly larger amounts of cytokines, chemokines, and growth factors upon stimulation than platelets of healthy subjects, and contribute to increased acute phase reactants (fibrinogen, vWF, and factor XII), indicating that platelets are primed to spread proinflammatory and procoagulant activities leading themselves to thrombosis in COVID-19 (67). The gene discussed is VWF; the disease is COVID-19.