Muscular dystrophy-causing dystroglycanopathies(i.e., Walker Warburg syndrome,WWS) associated with brain,eye/retinal defects, lissencephalyand PMG/agyria)type IIPOMGnT1 (#253280)POMT1 (#236670)POMT2 (#613150)POMK (#615249)LARGE1 (#613154)FKRP (#613153)FKTN (#253800)B3GNT1 (#615287)B3GALNT2 (#615181)ISPD (CRPPA, #614643)TMEM5 (# 6150741)TMTC3 (#617255). The gene discussed is LARGE1; the disease is neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan.