Then, we constructed a ferroptosis-related gene prognostic index (FRGPI) to predict the DFS in PCa patients by calculating the risk score of each patient based on the following formula (expression [Exp] of each gene weighted by its corresponding LASSO regression coefficient): risk score =  E2F1 (Exp) ×  (0.05986576)  +  CDC20 (Exp)  ×  (0.25686091)  +  TYMS  (Exp) ×  (0.03883863)  +  NUP85  (Exp) ×  (0.97691510). Here, E2F1 is linked to posterior cortical atrophy.