A previous study has also shown that an almond-based low carbohydrate diet may improve glucose metabolism in patients with T2DM by increasing SCFA-producing bacteria, including Roseburia, Ruminococcus and Eubacterium, to elevate SCFA production and activate GPR43 to sustain GLP-1 secretion (48). Here, GLP1R is linked to type 2 diabetes mellitus.