CEACAM5 and neoplasm: These include short DFI, multiple pulmonary metastases, involvement of hilar or mediastinal lymph nodes, elevated CEA before metastasectomy, tumor size, patients older than 70 years, extrapulmonary metastatic lesions treated before pulmonary metastasectomy, synchronous presentation, advanced primary tumor stage and rectum localization (3, 5, 6, 13).