SNHG12 and acute respiratory distress syndrome: Therefore, by establishing a mouse ALI model, this study investigated whether lncRNA SNHG12 played a protective role in the process of ALI from the aspects of expression level, inflammatory response, cell permeability, cell apoptosis, target binding test, etc., and explored the effect of lncRNA SNHG12 activation on LPS-induced ALI and its development mechanism at the cellular molecular level.