Although IL-17A has been shown to play both protective and pathogenic roles in chronic P. aeruginosa infections (Gurczynski and Moore, 2018), its role in acute P. aeruginosa infections, such as acute respiratory distress syndrome and VAP, seems to be unclear (Orlov et al., 2017; De Winter et al., 2019; Wong et al., 2021). This evidence concerns the gene IL17A and ventilator-associated pneumonia.