CD40LG and infection: The potent antiviral activity was mediated by several encoded factors, including IL-2, IL-12, IFN-gamma, TNF-α, CD40 ligand (CD40L), membrane immunoglobulin (mIg), and (cytokine responsive gene 2) Crg-2 (Ramshaw et al., 1997), revealing the mechanism of bacteriocin in combating infection-induced inflammation induced by pathogens.