CHMP5 and infection: Following natural infection with SARS-CoV-1, anti-Spike and anti-nucleocapsid (N) antibodies appear to be the dominant humoral response in serum (Chang et al., 2004; Xu and Gao, 2004; Du et al., 2009), along with cellular responses (Xu and Gao, 2004; Du et al., 2009).